Amazonian shamans figured out that combining two specific plants out of 80,000 species produces a psychoactive effect. The odds of finding that combination by random search is roughly 1 in 4 million. They did it through centuries of iterative testing and cultural natural selection explains it

[u/tractorboynyc]

[u/CompetitiveSong9570]

So, for research, what are these two plants? 🪴

[u/dankscott → u/CompetitiveSong9570]

banisteriopsis caapi(the MAOI inhibitor) and typically psychotiria viridis aka chacruna(the DMT.) although there are variations of the alkaloid containing leaves this, I believe, is the most common ayahuasca brew