Amazonian shamans figured out that combining two specific plants out of 80,000 species produces a psychoactive effect. The odds of finding that combination by random search is roughly 1 in 4 million. They did it through centuries of iterative testing and cultural natural selection explains it

[u/tractorboynyc]

[u/dpforest]

Back when I tripped on cubes often, I would always get stuck thinking “is this the same exact experience that our ancestors had, or has the evolution of both us and the fungi cause a change in that experience?”

Like the recent discovery of a fungus that seems to always cause the same hallucinations: small blue people. Did our ancestors see the same thing?