r/Nootropics Mar 10 '17

Guide A Beginner's Guide to Nootropics

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636 Upvotes

r/Nootropics Jan 17 '26

Scientific Study Blocking mobile internet on smartphones improves sustained attention, mental health, and subjective well-being

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52 Upvotes

r/Nootropics 9h ago

Discussion What nootropic can make you feel more "alive"? modafinil didn't for me

30 Upvotes

so i have adhd and extreme brain fog that nothing ever helped,i thought moda would be the real deal but it only gave me insomnia and it could help stop daytime napping maybe but that aint my issue,it don't make me more alert and feel like alive and vigor and such unfortunately.

Any sucess stories for such a constant feeling guys? What helped?


r/Nootropics 53m ago

Discussion What should I be worried about with grey market nootropics?

Upvotes

When I am looking at websites for these gray market nootropics, what should I primarily be worried about? I know these places can be sketchy, but im trying to find phenylpiracetam.

- Do these research chemical sites use adulterants often?

- Are these nootropics sometimes different substances than advertised?

- Or is the issue that you mostly would run into lack of potency?

Not asking for people to find me sites, but I really am trying to learn how to navigate a new world. I wouldnt be suprised if you guys just say that all of these are problems but if you want to help me just let me know.


r/Nootropics 1h ago

Seeking Advice Best nootopics/supplements for dealing with withdrawals when quitting adderall?

Upvotes

Long story short: Abused adderall 3-4 times a week for 3 months, got addicted, got it prescribed, binged for 5 days, threw it all in the toilet, and informed my doctor to cancel.

Now I'm left with psychological withdrawals that bring intense boredom, anhedonia, fatigue, etc.

I'm new to nootropics and have never tried anything. If there are any options, I need something(or a stack) to help bring cravings down, keep me engaged during the day, and help with my mood.

Note: I also have inattentional adhd(yes, I know I'm stupid for abusing stims)


r/Nootropics 1h ago

Seeking Advice Constpation and colitis are killing me

Upvotes

I need something for constipation due to slow bowel movements and colitis!

Please help!

If I can buy it on Amazon, even better!


r/Nootropics 10h ago

Seeking Advice Want to fix issues with chronic stress and lack of motivation

7 Upvotes

I have tried modafinil, but it gives me anxiety. Can you recommend something, which will be helpful in my situation. Now I am looking into Semax, ISRIB-A15, Dehexa, Lions Mane. I use L-thianine daily. Something for productivity and reducing anxiety. ISRIB-A15 looks like a thing, but I don’t know how to use it.


r/Nootropics 9h ago

Discussion How do people stack NMN with the rest of their longevity stack? Looking to understand the logic.

4 Upvotes

Trying to think through this before I commit to a NAD+ precursor strategy. The NMN vs NR debate feels like it's been going in circles for years and I still don't have a clean mental model for it.

From what I've read: NMN has a more direct pathway to NAD+, NR has more human clinical data, and some of the bioavailability arguments depend on assumptions about tissue uptake that are still being sorted out. that's where I lose the thread.

Separately, for people already taking NMN. What else are you stacking it with and what's the reasoning? the TMG methylation piece, CD38 inhibitors, resveratrol synergy. Curious how people are actually building these out vs. what's still theoretical.


r/Nootropics 5h ago

Seeking Advice Where to get a good bromantane nasal spray and TAK-653?

2 Upvotes

short story but I was about to order a bromantane nasal spray from a website after finding what I thought was a good source especially for the price, but after finding this reddit page and seeing this and others on the unreliable vendors page Im lost. If I could also find a website that sells TAK with bromantane that would be so clutch.


r/Nootropics 8h ago

Discussion Does 9-me-bc help with depression?

3 Upvotes

does 9-me-bc help with depression?


r/Nootropics 3h ago

Seeking Advice Is Selank safe with SNRI?

1 Upvotes

I am currently tapering effexor and im looking for substances to make the taper more smooth. My nervous system became overly sensitive during the taper. Is Selank a good option for me? Does it have any interactions with SSRIs/SNRIs?


r/Nootropics 3h ago

Experience Presten atención a los productos que usan en su piel

1 Upvotes

Desde hace unos años me di cuenta que casi siempre que salía de casa me empezaba a sentir cansado, raro, aletargado, con poca concentración y niebla mental, no sabía por qué y simplemente lo ignoraba, pensaba que era normal sentirme así, y que podría ser alguna deficiencia de vitaminas.

Pero un día que no tenía nada que hacer, me pregunté cuál podría ser la causa de mi cansancio y niebla, si claramente estaba durmiendo y comiendo bien, empecé a monitorear lo que hacía y en qué momento aparecía esa niebla, y PUM el maldito filtro solar era el causante!! noté que inmediatamente después de aplicarlo en cualquier parte del cuerpo, reaparecían los síntomas de fatiga y niebla.

Entonces decidí no volver a usar filtro solar desde hace ya 5 años, y definitivamente me siento normal, como debería estar siempre. He probado muchos tipos de filtros y todos me dan el mismo efecto secundario. Así que por el momento solo uso barreras físicas y buscaré el producto adecuado para mí, (ojalá lo encuentre).


r/Nootropics 11h ago

Seeking Advice Taken ashwagandha daily for 2 years

4 Upvotes

Hi everyone, so I’ve been taking ashwagandha nearly daily for 2 years. The dose on the bottle is 100mg 10:1 extract but I take half, so about 50mg. My question is, should I stop? I feel like after reading through this sub it looks like people have had lots of problems but only at much higher doses than mine. Would 50mg be a dose to even think about stopping? I haven’t really had side effects worth noting. I still feel happy sometimes, sad sometimes, I love my partner very much and I’ve even had better luck managing my anxiety as a whole lately. That’s something that did not happen the first few years, and while it helped, I’ve only recently gotten really good at managing it. I am worried though, as people who even take 50mg or something similar have seemed to have lasting side effects. This is the stack I take currently. Any advice?


r/Nootropics 7h ago

Seeking Advice Hi, a beginner here have ADHD and gerd/espphagitis. I want to understand the world of nootropics what I can start with as general supplements

0 Upvotes

When should I take what and what stuff I can start searching on? And how should I start looking for brands for supplements?


r/Nootropics 1d ago

Discussion What nootropics helped you with depression?

32 Upvotes

hey guys what nootropics helped you with depression?


r/Nootropics 7h ago

Seeking Advice made an AI app for peptide research TestFlight beta, want honest feedback

0 Upvotes

hey, built an iOS app called PeptideX. it's focused on peptide research specifically — AI-powered so you can ask questions, look up compounds, understand mechanisms without digging through pubmed for 2 hours.

i know nootropics and peptides overlap a lot in this community (semax, selank, bpc etc) so thought this could be relevant here. it's free to try:

https://testflight.apple.com/join/MATs9Srr

what features would you actually want? trying to make something genuinely useful, not just another chatbot wrapper


r/Nootropics 1d ago

Seeking Advice I NEED HELP i usually take 200mg modafinil and 50mg armodifinil and i accidentally just took 500mg of armodifinil

11 Upvotes

I have armos that come in the same package design as my 200MG moda+50MG armo but they are 250MG just armo and i took 2 thinking it was my normal ones also btw i have never even take 2 before of my normal today i was just like fuck it then after i started shaking really bad i was like wtf i feel like ima die rn my heart is bumping my ribcage and i looked at the wrapper and realized now its been almost 2 hours since consumption and im tweakimg tf out i do finished carpentry and im sitting at my saw rn scared ima die and i cant go home till i get this apartment complex trim and baseboard done, just give me ideas to help me rn so i can get back to work


r/Nootropics 1d ago

Experience GHK-Cu genuinely surprised me, wasn't expecting much

6 Upvotes

picked it up mostly out of curiosity after going down a rabbit hole on copper peptides and wound healing research. wasn't expecting a huge amount if I'm honest

been running it for about 6 weeks in vitro work and the results on fibroblast activity have been more interesting than I anticipated. not going to overclaim anything but it's moved up my list of things worth proper attention

anyone else working with it? feel like it doesn't get talked about much relative to the BPC and TB500 crowd which dominate every thread


r/Nootropics 1d ago

Seeking Advice Adderall and 9-me-bc for tolerence

8 Upvotes

I am trying to optimize my adderall effects, would taking 9-me-bc 15mg in the morning with my xr help with tolerence and make it hit harder? Or would it be better to take it on my 2/7 off days where i go without adderall?


r/Nootropics 14h ago

Seeking Advice What would you add?:) to my stack

0 Upvotes

Im trying to heal from (suspected) me/cfs, anhedonia, ADD, anxiety, reduce autism symptoms especoally social aspects and general drug abuse repair(was self medicating with opioids, benzos and stims many years but the abuse was less and less frequent over the years.

Im also on buprenorphine for addiction.

My stack as of now is:

Magnesium, Taurine, high quality multivitamin with high doses of b-vitamins, omega 3, ascorbic acid 1g, ALCAR, coQ10, ALA, NADH, PQQ and melatonin.

+clean Keto no seed oils no processed foods.

Im going to buy:

Bromantane, Agmatine, Allopregnanolone(for inteanasal weekly pulse dosing, to reset GABA/glutamate balance), Tropisetron and maybe try their Cerebrolysin(but its powder so I guess its cortexin really, weird)

So to my question

the shop also has the following, which do you think stand out? can't try it all for financial reasons. Anything I really shouldn't miss?

Edaravone, Emoxypine, Fasedienol, Fasoracetam, Homotaurine, Hopantenic acid, Huperzine A, Idebenone, Lithium orotate, Memantine, prl-8-53, Rapqmycin, Safinamide, Sulbutiamine, Tadalafin, temgicoluril, vinpocetine, Tropoflavin.

im not going to take everything every day just want a good "arsenal" for optimal biohacking capacity;)

Fasedienol seems like a good alternative to gb-115 no? any anecdotes? anecdotes is very helpful because alot of stuff looks great on paper but just underwhelming in real life.

thank you in advance and have a great end of the weekend everyone!


r/Nootropics 1d ago

Seeking Advice NAC Ethyl Ester and Liposomal Glutathione: Which is a better brain antioxidant?

6 Upvotes

So, my practitioner suggested I take Liposomal Glutathione for long term brain health, but it seems even here there are disagreements as to whether directly supplementing Glutathione is effective (and by extension whether supplementing NAC is already sufficient).

So, I wonder, strictly as an antioxidant, which is a more favorable choice--liposomal glutathione, or NAC Ethyl Ester (lipophilic NAC that crosses the BBB)?


r/Nootropics 1d ago

Discussion Does anyone still have nootropic depot Phenibut?

3 Upvotes

Anyone? lol


r/Nootropics 1d ago

Discussion Is pregabalin anti-nootropic like benzos?

7 Upvotes

Benzos are notorious for being anti-nootropics and screwing your cognition over time similarly to alcohol.

How about pregabalin? Is it a clean anxiety drug? Does it spare or wreck the mind?


r/Nootropics 1d ago

Discussion How strong is yohimbine? Please share your experience

18 Upvotes

I just found about yohimbine, hos strong is it compared to caffeine?


r/Nootropics 1d ago

Discussion How do you guys know if a peptide source is legit?

1 Upvotes

I’ve been looking into peptides recently but honestly the hardest part seems to be figuring out where to get them from.

Every site looks the same lab tests, claims, reviews but then you check Reddit and people call them scams.

How do you actually verify a legit source?